Understanding Advanced Glycation End Products (AGEs)

Advanced Glycation End Products are a key factor in the aging process of our skin. These compounds form when sugars react with proteins within impact skin health, leading to various issues such as stiffness, loss of elasticity, breakdown of collagen¹, wrinkles and a dull, uneven texture. Moreover, AGEs are associated with increased redness², contributing to an overall aged appearance.

Advanced Glycation End Products are a key factor in the aging process of our skin. These compounds form when sugars react with proteins within impact skin health, leading to various issues such as stiffness, loss of elasticity, breakdown of collagen¹, wrinkles and a dull, uneven texture. Moreover, AGEs are associated with increased redness², contributing to an overall aged appearance.

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Glycation 101: Understanding the Basics
Glycation is a natural process where sugars bind to proteins, such as collagen and elastin, forming harmful substances called AGEs, which can stiffen proteins and accelerate visible signs of aging. Without intervention, glycated collagen accumulates with an average annual rate of 3.7%.

This process doesn't happen overnight. It's a gradual accumulation of damage that contributes to the visible signs of aging over time. High sugar foods can increase the generation of AGEs in your system. This highlights the importance of managing blood sugar levels through diet and lifestyle choices.

References
¹Lingyu Wang, Yanfei Jiang, Chunyue Zhao; The effects of glycation end-products on skin and potential anti-glycation strategies. April2, 2024. In press.
²2. PubMed Central. Lennert Van Putte, Sofie De Schrijver, Peter Moortgat. The effects of advanced glycation end products (AGEs) on dermal wound healing and scar formation: a systematic review. In press.