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AlphaRet overnight cream bottle over butterfly wings

Celebrate National Retinoid Week

Discover skinbetter science during our 3rd annual holiday, designed to educate on the benefits of retinoids and showcase the transformative power of AlphaRet, our best-selling collection.



5 products with a blue background

CELEBRATE NATIONAL RETINOID WEEK WITH AN EXCLUSIVE GIFT WITH PURCHASE


Spend $149 | Receive an Alpharet Discovery Kit ($60 value)
Spend $299 | Receive an AlphaRet Explore Kit ($106 value)
Spend $399 | Receive an AlphaRet Luxe Kit ($252 value)

LEARN MORE

CELEBRATE NATIONAL RETINOID WEEK
WITH AN EXCLUSIVE GIFT WITH PURCHASE


Spend $149 | Receive an Alpharet Discovery Kit ($60 value)
Spend $299 | Receive an AlphaRet Explore Kit ($106 value)
Spend $399 | Receive an AlphaRet Luxe Kit ($252 value)

LEARN MORE

OUR BEST-SELLING TECHNOLOGY, BELOVED FOR 10 YEARS


38 Industry Awards
16 Clinical Studies
15 Safety Studies
450+ Patients Tested
7 Peer-Reviewed Publications
Assortment of AlphaRet products with dark blue background

OUR BEST-SELLING TECHNOLOGY, BELOVED FOR 10 YEARS


38 Industry Awards
16 Clinical Studies
15 Safety Studies
450+ Patients Tested
7 Peer-Reviewed Publications
Retinoid guide - image of a graph that charts the retinoid prescription strength

NOT ALL RETINOIDS ARE CREATED EQUALLY.


How They Work:
They convert into retinoic acid on the skin to target visible signs of aging like fine lines and wrinkles. Each conversion step can reduce potency.

The Tradeoff:
Tretinoin is a prescription-retinoid that doesn’t require conversion steps but can irritate skin, which may lead to inconsistent use and limit results.

Retinol and Retinal, while often used interchangeably, are distinct compounds, have different conversion paths and different user-experiences.

Side effects of retinoids including redness, peeling, dryness, or burning.

NOT ALL RETINOIDS ARE CREATED EQUALLY.


How They Work:
They convert into retinoic acid on the skin to target visible signs of aging like fine lines and wrinkles. Each conversion step can reduce potency.

The Tradeoff:
Tretinoin is a prescription-retinoid that doesn’t require conversion steps but can irritate skin, which may lead to inconsistent use and limit results.

Retinol and Retinal, while often used interchangeably, are distinct compounds, have different conversion paths and different user-experiences.

Side effects of retinoids including redness, peeling, dryness, or burning.

EXPERIENCE A BE++ER RETINOID. ​
ALPHARET OVERNIGHT CREAM.​​


Clinically proven to fight lines while hydrating skin.​

Visible results in 4 weeks.​

From the #1 dermatologist recommended retinoid brand.*​ ​​

*Among non-prescription brands sold by physicians or medical practices, in addition to other outlets or retailers. Blinded nationwide survey of dermatologists 2025. Responding dermatologists may have sales relationships with one or more medical aesthetic brands.
Butterfly wings behind an AlphaRet Overnight bottle

EXPERIENCE A BE++ER RETINOID. ALPHARET OVERNIGHT CREAM.​​


Clinically proven to fight lines while hydrating skin.​

Visible results in 4 weeks.​

From the #1 dermatologist recommended retinoid brand.*​ ​​

*Among non-prescription brands sold by physicians or medical practices, in addition to other outlets or retailers. Blinded nationwide survey of dermatologists 2025. Responding dermatologists may have sales relationships with one or more medical aesthetic brands.

EXPERIENCE TRANSFORMATIVE, ANTI-AGING RESULTS​


​ ​-33% Reduction of the appearance of fine lines and wrinkles**​

​+14% ​Increase in skin hydration** ​

97% Agree AlphaRet feels gentle for daily use**​ ​

*Average Result​
**A 12-week split-face, randomized, dermatologist-led clinical study in participants with mild-to-severe photoaging. N=48​

EXPERIENCE TRANSFORMATIVE, ANTI-AGING RESULTS​


​ ​-33% Reduction of the appearance of fine lines and wrinkles**​

​+14% ​Increase in skin hydration** ​

97% Agree AlphaRet feels gentle for daily use**​ ​

*Average Result​
**A 12-week split-face, randomized, dermatologist-led clinical study in participants with mild-to-severe photoaging. N=48​
"AlphaRet has been my favorite Retinoid since its inception. This innovative retinol molecule combined with Lactic acid, (AHA) peptides and a blend of antioxidants is my go-to product for improving fine lines, wrinkles, uneven tone, and texture with minimal irritation. Patients love the product and often combine it with Alto Advanced Defense and Repair serum and Even tone correcting serum to address all of their skin care needs! A dynamic trio." 

-Natalie Curcio, MD, MPH, MMHC
Person with AlphaRet product

"AlphaRet has been my favorite Retinoid since its inception. This innovative retinol molecule combined with Lactic acid, (AHA) peptides and a blend of antioxidants is my go-to product for improving fine lines, wrinkles, uneven tone, and texture with minimal irritation. Patients love the product and often combine it with Alto Advanced Defense and Repair serum and Even tone correcting serum to address all of their skin care needs! A dynamic trio." 

-Natalie Curcio, MD, MPH, MMHC

Shop the AlphaRet Collection

Establish Your Personalized Regimen​

Unique skin types and concerns require a personalized approach. When a qualified skincare professional thoughtfully curates your regimen, it can result in healthier, more radiant-looking skin.​

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